NAFLD Fibrosis Score

Non-invasive score to identify advanced fibrosis in patients with non-alcoholic fatty liver disease (NAFLD/MASLD).

years

Age in years

kg/m2

Body mass index

IFG or diabetes mellitus present (yes=1, no=0)

U/L

Aspartate aminotransferase

U/L

Alanine aminotransferase

10^9/L

Platelet count

g/dL

Serum albumin in g/dL

Clinical Notes & Warnings

  • Validated for adults only; not for children or pregnant women.
  • May overestimate fibrosis risk in patients >=65 years.
  • Not for acute hepatitis.
  • NICE NG49 recommends ELF test as preferred first-line assessment.

Score typically ranges from -3.0 to +3.0. Cutoffs: <-1.455 low risk, -1.455 to 0.676 intermediate, >0.676 high risk.