Ranson Criteria
Predicts severity and mortality of acute pancreatitis using criteria at admission and at 48 hours.
Age at admission >55 (alcoholic) or >70 (gallstone)
White blood cell count >16,000/mm3 (>18,000 for gallstone)
Blood glucose >200 mg/dL (>220 for gallstone)
Serum AST >250 IU/L
Serum LDH >350 IU/L (>400 for gallstone)
Serum calcium <8.0 mg/dL at 48h
Hematocrit decrease >10% at 48h
Arterial PaO2 <60 mmHg at 48h
BUN increased by >=5 mg/dL (>=2 for gallstone) despite IV hydration
Base deficit >4 mEq/L (>5 for gallstone) at 48h
Fluid sequestration >6L (>4L for gallstone) at 48h
References
- Ranson Criteria - StatPearls - NCBI Bookshelf
- Severity Scoring for Prognostication in Patients With Acute Pancreatitis - JAMA Surgery
Clinical Notes & Warnings
- Cannot be fully determined until 48 hours after admission.
- Less useful than BISAP or APACHE-II for early prediction.
- Not validated for pediatric patients.
- Different cutoffs for alcoholic vs gallstone pancreatitis.
Modified Ranson criteria for gallstone pancreatitis have different thresholds. BISAP is preferred for early assessment.