Cerebral Perfusion Pressure (CPP)

Calculates the pressure gradient driving cerebral blood flow. Critical for managing traumatic brain injury and intracranial hypertension.

mmHg

Mean arterial pressure in mmHg

mmHg

Intracranial pressure in mmHg (normal 5-10)

Enter MAP and ICP to calculate CPP

References

  1. Cerebral Perfusion Pressure - StatPearls - NCBI Bookshelf / NIH
  2. Cerebral Perfusion Pressure in TBI - Life in the Fast Lane

Clinical Notes & Warnings

  • Target CPP is 60-70 mmHg for severe TBI per BTF guidelines (4th edition).
  • Some guidelines suggest 50-70 mmHg range.
  • Autoregulation may be impaired in injured brain; optimal CPP may be patient-specific.
  • Requires invasive ICP monitoring for accuracy.

Alternative formula: CPP = MAP - CVP (use CVP if higher than ICP). Normal CPP is 60-80 mmHg.