Neuropathic Pain Dosing Calculator

Renal-adjusted dosing for gabapentin and pregabalin.

Dr. Taimoor Asghar
Medically reviewed by Dr. Taimoor Asghar, MBBS Last updated:

Neuropathic Pain Dosing Form

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Understanding Your Results

Both gabapentin and pregabalin are renally excreted. Dosing must be adjusted in patients with reduced creatinine clearance to avoid neuropsychiatric side effects and sedation. Recommendations are general guidelines; always verify with current prescribing information.

CrCl RangeGabapentin GuidancePregabalin Guidance
≥60 mL/minStart 300 mg TID. Max 3600 mg/day.Start 75 mg BID or 50 mg TID. Max 600 mg/day.
30–59 mL/minStart 200–700 mg BID. Max 1400 mg/day.Start 75 mg QD or BID. Max 300 mg/day.
15–29 mL/minStart 200–700 mg QD. Max 700 mg/day.Start 25–50 mg QD. Max 150 mg/day.
<15 mL/minStart 100–300 mg every other day.Start 25 mg QD. Max 75 mg/day.
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Frequently Asked Questions

What is this calculator used for?

This calculator helps estimate clinical values, risks, or dosing based on validated formulas and guidelines.

How accurate are the results?

Results are estimates and should always be confirmed with clinical judgment and appropriate testing.

Can I use this for pediatric patients?

Follow the specific calculator instructions. Some tools are pediatric-specific, while others are for adults only.

When should I contact a doctor?

Always consult a healthcare provider for abnormal results, worsening symptoms, or if you are unsure about next steps.