MELD-Na: Model for End-Stage Liver Disease — Sodium

3-month mortality in advanced liver disease; transplant prioritization. Free to use.

gastroenterology, hepatology 5 items Updated 2026-05-05

Score MELD-Na below → Download printable PDF View source paper (DOI)
What is MELD-Na? MELD-Na (Model for End-Stage Liver Disease — Sodium) is a validated instrument used to assess 3-month mortality in advanced liver disease; transplant prioritization. It comprises 5 items.

What is MELD-Na?

MELD-Na (Model for End-Stage Liver Disease — Sodium) is a validated clinical instrument used to assess 3-month mortality in advanced liver disease; transplant prioritization. The instrument contains 5 items.

Source / attribution: Kim WR et al., NEJM 2008 (UNOS implementation 2016)

Clinical context: when MELD-Na is used

Like all screening or assessment instruments, MELD-Na is a structured aid — not a diagnostic test in isolation. Results should be interpreted alongside history, examination, and clinical context. Where a score crosses an actionable threshold, the next step is typically a more detailed clinical evaluation rather than a definitive diagnosis.

Score MELD-Na

Answer all 5 items below to see your MELD-Na score and interpretation.

All scoring runs in your browser. No data is sent anywhere — close the tab and the answers are gone.

How MELD-Na is scored

MELD-Na uses a published formula (meld-na) rather than simple summation. The formula and its inputs are visible in our open-source scoring engine.

Scoring notes: Educational use only. Floors and caps applied per UNOS rules.

MELD-Na score interpretation

The cutoffs below are drawn from the published validation literature. Always interpret in clinical context.

Score rangeBandInterpretation
6–9LowLower mortality risk.
10–19ModerateModerate mortality risk.
20–29HighHigh mortality risk.
30–40Very highVery high mortality risk.

How to score MELD-Na: worked example

MELD-Na uses a published formula rather than simple summation. Below is a step-by-step calculation with illustrative inputs.

Step 1 — Collect the inputs

InputValue
Bilirubin2.0 mg/dL
INR1.5
Creatinine1.5 mg/dL
Sodium135 mEq/L

Step 2 — Apply the formula

  1. Bound each value to the safe range. Lab values below 1.0 are floored to 1.0; sodium is bounded to 125–137.
  2. Compute the original MELD: MELD = 3.78 × ln(2.0) + 11.2 × ln(1.5) + 9.57 × ln(1.5) + 6.43 ≈ 17.5
  3. Apply the sodium correction (only if Na < 137): MELD-Na = 17.5 + 1.32 × (137 − 135) − 0.033 × 17.5 × (137 − 135) ≈ 19
  4. Round to the nearest integer and clamp to 6–40.

Step 3 — Read the result

Score = 19 → Moderate — Moderate mortality risk.

Use the calculator above with your own values →

Limitations & common pitfalls

How MELD-Na compares to other gastroenterology scales

If MELD-Na doesn't fit your context, related instruments in gastroenterology include:

ScaleMeasuresItemsTime
Child-PughSeverity of cirrhosis and prognosis5—
Glasgow-BlatchfordPre-endoscopy risk in upper GI bleeding9—
ASA Physical StatusPre-operative health status1—
Barthel IndexFunctional independence in ADLs10—
BDI-IISeverity of depression—≈ 5 minutes
CHA2DS2-VAScAnnual stroke risk in non-valvular atrial fibrillation8—
CURB-6530-day mortality in community-acquired pneumonia5—
Glasgow Coma ScaleLevel of consciousness after head injury3—

Frequently asked questions about MELD-Na

What does MELD-Na measure?

MELD-Na (Model for End-Stage Liver Disease — Sodium) is a validated instrument that assesses 3-month mortality in advanced liver disease; transplant prioritization. It is designed for clinicians, medical students, evidence-synthesis researchers. The 5 items are combined to produce a total score.

How many items are on MELD-Na?

MELD-Na contains 5 items. Items feed into a scoring formula that produces the total. Scores run from 6 to 40, grouped into 4 interpretation bands from ‘Low’ up to ‘Very high’.

What is a high MELD-Na score?

On the MELD-Na (total score 6–40), scores of 30–40 fall in the ‘Very high’ band — interpreted as: Very high mortality risk. The full ladder is: 6–9 — Low: Lower mortality risk.; 10–19 — Moderate: Moderate mortality risk.; 20–29 — High: High mortality risk.; 30–40 — Very high: Very high mortality risk. A higher score reflects a more severe presentation, and crossing a cutoff is a prompt to step up assessment or care — but these bands are screening thresholds, not diagnoses.

What is a low MELD-Na score?

Scores of 6–9 fall in the ‘Low’ band: Lower mortality risk. A low score is reassuring but does not by itself rule out the underlying condition — if symptoms or clinical suspicion persist, reassess over time or use a complementary evaluation rather than relying on the number alone.

Is MELD-Na free to use?

Yes — MELD-Na is in the public domain and free for clinical, educational, and research use without permission. You can use this calculator and the scale itself freely; if you publish results or reproduce the scale, cite the original source paper.

What is the source paper for MELD-Na?

Kim WR et al. N Engl J Med. 2008;359(10):1018-1026. This is the original publication for the MELD-Na — the reference to cite when reporting results.

Can MELD-Na replace clinical judgment?

No. MELD-Na is a structured assessment aid, not a diagnostic test. Its proper role is clinical assessment of 3-month mortality in advanced liver disease; transplant prioritization — it standardizes assessment and flags who needs closer evaluation, but the result must be weighed alongside history, examination, and clinical context. When a score conflicts with your clinical impression, clinical judgment takes precedence; treatment decisions should never rest on a screening score alone.

References & validation

MELD-Na is supported by the following peer-reviewed sources: