Neonatal Jaundice Bilirubin Risk Nomogram

Determines phototherapy and exchange transfusion thresholds for neonatal hyperbilirubinemia based on AAP 2004 or 2022 guidelines.

mg/dL

Total serum bilirubin level

hours

Postnatal age in hours

weeks

Gestational age at birth in completed weeks

Risk factors that lower treatment thresholds

AAP guideline version for threshold calculation

⚠️ Warnings & Contraindications

  • AAP 2022 raised phototherapy thresholds for healthy term infants compared to 2004
  • Universal bilirubin screening recommended before discharge for infants >=35 weeks
  • Transcutaneous bilirubin (TcB) can be used for screening; confirm elevated TcB with serum TSB
  • Infants <35 weeks gestation have lower thresholds
  • Rapidly rising bilirubin (>0.3 mg/dL/hour or >5 mg/dL in 24 hours) requires urgent evaluation
  • Use hour-specific nomogram, not day-specific

ℹ️ Clinical Notes

The AAP 2022 guideline eliminated race as a risk factor, recommends universal screening, and uses gestational age separate from neurotoxicity risk factors. The Bhutani nomogram (2004) hour-specific percentile curves are commonly used.

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