Omeprazole Pediatric Dosing
Proton pump inhibitor dosing for GERD, erosive esophagitis, and H. pylori eradication in children.
Weight in kilograms
Age in years
Clinical indication
⚠️ Warnings & Contraindications
- Increased risk of GI infections (C. difficile, pneumonia) with prolonged use
- May affect absorption of iron, calcium, vitamin B12
- Increased fracture risk with long-term high-dose use
- Not routinely recommended for uncomplicated infant GERD/spitting up
- Do NOT crush delayed-release pellets - may be sprinkled on soft food
- Rebound acid hypersecretion may occur after discontinuation
ℹ️ Clinical Notes
Delayed-release capsules: 10 mg, 20 mg, 40 mg. Oral suspension can be compounded (2 mg/mL). Powder for suspension (Zegerid): 20 mg, 40 mg packets. Take before meals. Lansoprazole and esomeprazole are alternative PPIs with pediatric formulations.
References
- Omeprazole pediatric dosing - Drugs.com (2026)
- PPI use in infants and children - AAP - AAP (2020)
Medical Disclaimer
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